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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
45.76
Human Site:
S846
Identified Species:
77.44
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
S846
L
Q
F
F
Q
D
V
S
D
R
I
E
K
E
S
Chimpanzee
Pan troglodytes
XP_511585
968
108684
S831
L
Q
F
F
Q
D
V
S
D
R
I
E
K
E
S
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
S939
L
Q
F
F
Q
D
V
S
D
R
I
E
K
E
S
Dog
Lupus familis
XP_853409
975
109686
S844
L
Q
F
F
Q
D
V
S
D
R
I
E
K
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
S846
L
Q
F
F
Q
D
V
S
D
R
I
E
K
E
A
Rat
Rattus norvegicus
XP_573211
965
109012
S834
L
Q
F
F
Q
D
V
S
D
R
I
E
K
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
S807
L
Q
F
F
Q
D
V
S
D
R
I
E
K
E
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
S837
L
Q
F
F
Q
D
V
S
D
R
I
E
K
E
P
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
Q796
F
F
W
S
P
E
K
Q
L
Q
F
F
Q
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
S826
L
S
F
L
Q
D
V
S
D
R
V
E
K
L
Q
Honey Bee
Apis mellifera
XP_392044
968
110555
S797
V
E
K
E
E
T
S
S
P
A
L
L
A
L
E
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
S802
V
E
K
E
E
D
N
S
P
V
V
R
R
I
E
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
S862
L
A
F
F
Q
D
V
S
D
R
I
E
K
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
S994
L
E
F
L
L
K
V
S
D
R
L
E
I
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
100
N.A.
93.3
0
N.A.
66.6
6.6
13.3
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
33.3
N.A.
73.3
33.3
46.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
79
0
0
79
0
0
0
0
8
0
% D
% Glu:
0
22
0
15
15
8
0
0
0
0
0
79
0
72
15
% E
% Phe:
8
8
79
65
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
65
0
8
8
0
% I
% Lys:
0
0
15
0
0
8
8
0
0
0
0
0
72
0
0
% K
% Leu:
79
0
0
15
8
0
0
0
8
0
15
8
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
8
0
0
0
15
0
0
0
0
0
15
% P
% Gln:
0
58
0
0
72
0
0
8
0
8
0
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
79
0
8
8
0
0
% R
% Ser:
0
8
0
8
0
0
8
93
0
0
0
0
0
0
43
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
15
0
0
0
0
0
79
0
0
8
15
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _